Annual report pursuant to Section 13 and 15(d)

COMMITMENTS AND CONTINGENCIES (Details)

v3.22.1
COMMITMENTS AND CONTINGENCIES (Details)
12 Months Ended
Apr. 01, 2019
USD ($)
Dec. 19, 2012
USD ($)
Dec. 31, 2021
USD ($)
Term
Facility
Tranche
Center
Dec. 31, 2020
USD ($)
Jun. 15, 2022
USD ($)
Sep. 30, 2021
USD ($)
Vendor and Licensor Commitments [Abstract]            
Number of FDA inspections completed | Facility     2      
Plasma supply agreement term     10 years      
Post-Marketing Commitments [Abstract]            
Amount of expenses to complete studies $ 2,000,000   $ 3,646,060 $ 5,907,013    
Other Commitments [Abstract]            
Number of tranches | Tranche     2      
Compensation expense period     15 years      
Revenue Benchmark [Member] | Customer Concentration Risk [Member] | International Customers [Member]            
Vendor and Licensor Commitments [Abstract]            
Concentration risk, percentage     13.00% 13.00%    
Maximum [Member]            
Post-Marketing Commitments [Abstract]            
Amount of expenses to complete studies   $ 4,000,000.0        
Minimum [Member]            
Post-Marketing Commitments [Abstract]            
Amount of expenses to complete studies   $ 3,000,000.0        
Employee Retention Program [Member]            
Other Commitments [Abstract]            
Retention amount paid to employees, tranche one           $ 1,300,000
Amount of first tranche recognized over the retention service period           $ 800,000
Employee Retention Program [Member] | Plan [Member]            
Other Commitments [Abstract]            
Retention amount payable to employees, second tranche         $ 1,300,000  
2011 Plasma Purchase Agreement [Member]            
Vendor and Licensor Commitments [Abstract]            
Plasma purchase agreement term     10 years      
Number of renewal terms | Term     2      
Plasma purchase agreement renewal period     5 years      
Number of plasma collection centers transferred to BPC | Center     2      
Percentage of plasma purchase price equal to cost     5.00%      
2011 Plasma Purchase Agreement [Member] | Maximum [Member]            
Vendor and Licensor Commitments [Abstract]            
Number of plasma collection facilities | Facility     5      
2017 Plasma Purchase Agreement [Member]            
Vendor and Licensor Commitments [Abstract]            
Number of plasma collection facilities | Facility     10      
Plasma purchase agreement term     5 years      
Number of renewal terms | Term     2      
Plasma purchase agreement renewal period     2 years