Quarterly report pursuant to Section 13 or 15(d)

STOCKHOLDERS' EQUITY, Equity Incentive Plans (Details)

v3.21.2
STOCKHOLDERS' EQUITY, Equity Incentive Plans (Details) - USD ($)
 3 Months Ended 9 Months Ended
Sep. 28, 2021
Sep. 30, 2021
Sep. 30, 2020
Sep. 30, 2021
Sep. 30, 2020
Restricted Stock Units [Abstract]          
Restricted stock units vested over a period       4 years  
Total stock-based compensation expense, Amount [Abstract]          
Total stock-based compensation expense   $ 688,274 $ 774,784 $ 2,274,860 $ 2,166,940
Research and Development [Member]          
Total stock-based compensation expense, Amount [Abstract]          
Total stock-based compensation expense   1,526 166,610 149,232 365,213
Plasma Center Operating Expenses [Member]          
Total stock-based compensation expense, Amount [Abstract]          
Total stock-based compensation expense   14,150 8,579 38,605 24,333
Selling, General and Administrative [Member]          
Total stock-based compensation expense, Amount [Abstract]          
Total stock-based compensation expense   596,084 535,949 1,850,411 1,599,094
Cost of Product Revenue [Member]          
Total stock-based compensation expense, Amount [Abstract]          
Total stock-based compensation expense   76,514 $ 63,646 236,612 $ 178,300
Equity Incentive Plans [Member]          
Stock Options, Weighted Average Exercise Price [Abstract]          
Unrecognized compensation expense, stock options   $ 3,700,000   $ 3,700,000  
Unrecognized compensation expense recognition period       2 years 6 months  
Stock Options [Member]          
Fair Value Assumptions and Methodology [Abstract]          
Volatility       69.00%  
Dividend yield       0.00% 0.00%
Stock Options [Abstract]          
Number of stock options granted (in shares)       1,757,050 1,398,412
Weighted average remaining contractual life of stock options, outstanding       6 years 3 months 18 days  
Weighted average remaining contractual life of stock options, expected to vest       6 years 3 months 18 days  
Weighted average remaining contractual life of stock options, exercisable       5 years 1 month 6 days  
Stock Option, Shares [Abstract]          
Options outstanding, vested and expected to vest, beginning balance (in shares)       6,922,931  
Forfeited (in shares)       (433,492)  
Expired (in shares)       (414,867)  
Granted (in shares)       1,757,050  
Exercised (in shares)       0  
Options outstanding, vested and expected to vest, ending balance (in shares)   7,831,622   7,831,622  
Options exercisable (in shares)   5,261,720   5,261,720  
Stock Options, Weighted Average Exercise Price [Abstract]          
Options outstanding, vested and expected to vest, weighted average exercise price, beginning balance (in dollars per share)       $ 4.40  
Forfeited, weighted average exercise price (in dollars per share)       2.96  
Expired, weighted average exercise price (in dollars per share)       4.96  
Granted, weighted average exercise price (in dollars per share)       2.22  
Exercised, weighted average exercise price (in dollars per share)       0  
Options outstanding, vested and expected to vest, weighted average exercise price, ending balance (in dollars per share)   $ 3.96   3.96  
Options exercisable, weighted average exercise price (in dollars per share)   $ 4.62   $ 4.62  
Stock Options [Member] | Minimum [Member]          
Fair Value Assumptions and Methodology [Abstract]          
Expected term       5 years 6 months 5 years 6 months
Volatility         62.00%
Risk-free interest rate       0.80% 0.33%
Stock Options [Member] | Maximum [Member]          
Fair Value Assumptions and Methodology [Abstract]          
Expected term       6 years 3 months 18 days 6 years 3 months 18 days
Volatility         69.00%
Risk-free interest rate       1.14% 1.68%
Restricted Stock Units (RSUs) [Member]          
Restricted Stock Units [Abstract]          
Number of restricted stock units granted (in shares) 3,780,000     4,332,244 361,000
Shares withheld for tax withholding obligation (in shares)   27,850   27,850  
Amount of shares withheld for tax withholding obligation   $ 62,000   $ 62,000  
Unvested RSU, Shares [Abstract]          
Beginning balance (in shares)       326,000  
Granted (in shares)       4,332,244  
Vested (in shares)       (92,750)  
Forfeited (in shares)       (96,361)  
Ending balance (in shares)   4,469,133   4,469,133  
Unvested RSU, Weighted Average Grant Date Fair Value          
Unvested, Weighted average grant date fair value, beginning balance (in dollars per share)       $ 2.81  
Granted, Weighted average grant date fair value (in dollars per share)       1.30  
Vested, Weighted average grant date fair value (in dollars per share)       2.82  
Forfeited, Weighted average grant date fair value (in dollars per share)       2.53  
Unvested, Weighted average grant date fair value, ending balance (in dollars per share)   $ 1.35   $ 1.35  
Restricted Stock Units (RSUs) [Member] | Directors [Member]          
Restricted Stock Units [Abstract]          
Restricted stock units vested over a period       1 year  
Restricted Stock Units (RSUs) [Member] | Employees [Member]          
Restricted Stock Units [Abstract]          
Restricted stock units vested over a period       4 years  
Restricted Stock Units (RSUs) [Member] | Equity Incentive Plans [Member]          
Stock Options, Weighted Average Exercise Price [Abstract]          
Unrecognized compensation expense recognition period       2 years 9 months 18 days  
Unvested RSU, Weighted Average Grant Date Fair Value          
Unrecognized compensation expense, non option   $ 5,800,000   $ 5,800,000  
Time Based Restricted Stock (RSUs) [Member]          
Restricted Stock Units [Abstract]          
Number of restricted stock units granted (in shares) 2,632,500        
Time Based Restricted Stock (RSUs) [Member] | Tranche One [Member]          
Restricted Stock Units [Abstract]          
Vesting percentage of RSUs granted under retention bonus program 50.00%        
Milestone Based Restricted Stock (RSUs) [Member]          
Restricted Stock Units [Abstract]          
Number of restricted stock units granted (in shares) 1,147,500