Quarterly report pursuant to Section 13 or 15(d)

4. STOCKHOLDERS' EQUITY (Tables)

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4. STOCKHOLDERS' EQUITY (Tables)
3 Months Ended
Mar. 31, 2016
Equity [Abstract]  
Schedule of assumptions used for equity compensation expense
    Three Months Ended     Three Months Ended  
    March 31, 2016     March 31, 2015  
Expected term   5.8 - 6.3 years     6.3 years  
Volatility     52%       56-57%  
Dividend yield     0.0       0.0  
Risk-free interest rate     1.75-1.79%       1.49-1.90%  
Schedule of stock options outstanding
    Three Months Ended  
    March 31, 2016  
          Weighted  
          Average  
          Exercise  
    Shares     Price  
             
Outstanding at beginning of period     1,464,203     $ 8.02  
                 
Forfeited     (2,584 )   $ 8.25  
Granted     85,984     $ 5.97  
                 
Outstanding at end of period and expected to vest     1,547,603     $ 7.91  
                 
Options exercisable     994,085     $ 7.40  
Stock-based compensation expense
    Three Months Ended  
    March 31,  
    2016     2015  
             
Research and development   $ 156,556     $ 164,068  
Plasma centers     13,010       11,033  
General and administrative     252,614       211,968  
Total stock-based compensation expense   $ 422,180     $ 387,069