Annual report pursuant to Section 13 and 15(d)

9. STOCK OPTIONS (Tables)

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9. STOCK OPTIONS (Tables)
12 Months Ended
Dec. 31, 2015
Equity [Abstract]  
Schedule of stock options outstanding
    Year Ended     Year Ended  
    December 31, 2015     December 31, 2014  
          Weighted           Weighted  
          Average           Average  
          Exercise           Exercise  
    Shares     Price     Shares     Price  
                         
Outstanding at beginning of year     1,048,927     $ 7.24       826,995     $ 6.90  
                                 
Forfeited     (9,710 )   $ 9.16       -       -  
Exercised     (7,514 )   $ 6.55       -       -  
Granted     432,500     $ 9.92       221,932     $ 8.50  
Outstanding at end of year and expected to vest     1,464,203     $ 8.02       1,048,927     $ 7.24  
Options exercisable     880,457     $ 7.19       635,763     $ 6.81  
                                 
Weighted average fair value of options                                
granted during the year           $ 5.25             $ 5.06  
Stock-based compensation expense
    2015     2014  
             
Research and development   $ 724,776     $ 541,140  
Plasma centers     48,386       56,900  
General and administrative     937,885       650,414  
Total stock-based compensation expense   $ 1,711,047     $ 1,248,454